Jones Knuckles consist of two knuckles, the femur and the saddle. These are both knuckles from a USA beef femur bone, dipped in natural liquid smoke and oven baked with no artificial ingredients. Meat on the knuckles is purposely left on for a better chewing experience. The soft knuckle cartilage is a delicious treat and the bone left leaves a long-lasting chew. Plus its fun to say Jones Knuckle Bones. :) This natural chew is best for medium to large dogs. All Jones products are 100% grown and made in America.